Abstract: In order to solve the problem of low energy efficiency and low work efficiency in existing explosive welding, a new multi-layer explosive welding technology was proposed. In the case of five-layer explosive welding, 304 stainless steel and Q235 steel were used for flyer plate and base plate respectively. Comparison tests of multi-layer explosive welding and existing single-layer explosive welding were carried out. The explosive welding window and the impact velocity of the flyer plate were calculated theoretically. The result showed that energy utilization of the five-layer explosive welding increased by 63% compared to the existing explosive welding technology, and the five-layer explosive welding technology obtained five welded plates through one shot, which improved the working efficiency of the explosive welding. In addition, the explosive welding window of SUS304/Q235 was obtained and the welding quality was predicted, the experiment and prediction were in good agreement.