Abstract: The vacuum brazing of C/C-Re composite toNbwas successfully performed with the brazing fillers of Zr-Ni (atomic ratio 64:36) powder. The results show that the interface structures of joints with Zr-Ni fillers each has a total of four reaction layers. The microstructure of the C/C-Re/Zr-Ni/Nb joints is C/C-Re composite /Re/ (Re,Zr,Nb)+NiZr/NiZr2+NiZr/NiZr+Nb/Nb.Through dissolution process, the Re(Rhenium) coating became thinner and the (Re,Zr,Nb) solid solution increased. The joint mechanical properties are evaluated through joint shear strength test, and the conclusions are that the shear strength ofjoints rose up at first and then declined with the increase of brazing temperature and the extending of holding time.The optimum welding parameters are that the brazing temperature is 1 110 ℃ and the holding time is 20 min. Under the optimum welding parameters, the maximum environment temperature shear strength of joints with Zr-Ni fillers is 19 MPa.