Abstract: In order to optimize the control for flying-type flash-butt welder in an EBROS (endless-bar rolling system)before its physical prototype was made, a virtual prototype for the welder had been established.According to welder's working characteristics in the system, a control plan had been used that welder's moving velocity and its displacement were controlled in subsection.In order to improve the performance for welder running after rolled-billet in its forward travel, reduce mechanical couplings between welder and rolled-billet, and strengthen welder's capability of withstanding disturbances from outside, a composite controller of single nerve-cell based on an artificial immune adjusting law had been applied.Simulating results show that subsection control for the welder can meet its requirements of velocity in forward travel and its requirements of displacement in return travel, a composite controller of single nerve-cell can effectively increase synchronous-precision of welder tracking rolled-billet, and the introduction of an artificial immune adjusting law in the welder driving system can obviously enhance the property of welder resisting outside disturbances.