Abstract: The surface self-nanocrystallinzation was applied to ends of 0Cr18Ni9Ti stainless steel and TA17 near α titanium alloy bars by means of high energy shot peening(HESP), nanostructured surface layers on the ends of samples were obtained.Pulse-pressuring diffusion bonding (PPDB) of 0Cr18Ni9Ti stainless steel and TA17 titanium alloy with nanostructured layers was carried out at 825℃within 180 s.Tighten diffusion bonding joint of 0Cr18Ni9Ti and TA17 which tensile strength is 221.6 MPa were formed.And the atomic diffusion concentrations near interface were measured by using energy spectrometer.The diffusion coefficient of Fe atom during diffusion bonding in TA17 titanium alloy was achieved, the result shows that the diffusion coefficient of atoms during short-time diffusion bonding can be enhanced after 0Cr18Ni9Ti stainless steel and TA17 near α titanium alloy were treated.