Abstract: It is a major issue to reduce and control the welding deformation in the process of manufacturing the bogie frame of the high-speed locomotive.In this paper,heat-elastic-plastic mechanics was proposed to establish heating-elastic-plastic simulation model of the weld beam based on heating-mechanical coupling algorithm.The welding deformation with different welding sequences for inner welds and main welds were investigated with Marc.The results of finite element compution was applied to reduce welding deformation and quality control in manufacturing the bogie frame of the high-speed locomotive.To avoid the problem of low efficiency in such large complicated simulation model,the following strategies were taken in establishing the simulation model,such as the subsection moving string heat source model,parallel-treatment calculation technique and so on,which could catch the main relationship in the most complicated welding process simulation so that the conclusions were able to be applicable in the real engineering problems.