Abstract: In order to meet the industrialized requirement, the explosive bonding for large and thick stainless steel with billet was experimentally investigated. The explosive bonding parameters were calculated and optimized before experiment. It has shown that the calculated parameters prefigure exactly the explosive welding windows for stainless steel/mild steel. Simultaneously, the explosive speed as the accelerated distance from detonated point is greatly affected by the both explosive charge thick and area. The data obtained from experiment will be useful to industrialization of explosive bonding for large and thick stainless steel with billet.