Abstract: Titanium/aluminum composite plate with excellent performance can be obtained by combining thin layer titanium alloy plate with aluminum alloy plate, which has broad application prospects. TC1/1060/6061 composite plate was successfully prepared by explosive welding technology. The interface morphology and interface elements of the two interfaces were tested, and the advantages of 1060 interlayer were analyzed. At the same time, the finite element model consistent with the test conditions was established, and the interface state and welding process were analyzed. Finally, tensile test and shear test were carried out to verify the bonding quality of interface. The results show that the TC1/1060 interface has a linear morphology, and the 1060/6061 interface has a large wavy interface, and each wave is accompanied by the vortex region. The element diffusion range at the TC1/1060 interface is 4.38 μm, and no Ti/Al intermetallic compounds are detected. The numerical simulation reproduces the jetting formation in the process of explosive welding. The interface temperature is distributed along the interface morphology, and the interface pressure reaches the maximum at the collision point, showing an elliptic distribution. The composite plate has high tensile strength and shear strength, which can meet the requirements of structure use.