Abstract: To solve technical problems of low weldability and easy generation of brittle intermetallic compounds during titanium-aluminum explosive welding, the low-detonation-velocity powdery emulsion explosive, lower limit of charge thickness and upper limit of distance between the flyer and base plates were determined, thereby successfully manufacturing "1 + 14 + 1" TA2-1060-TA2 double-sided metal cladding plate with 100% welding rate. The results of OM, SEM, EDS tests showed that the interfaces of the cladding plate presented the high quality small wavy bonding; under the action of peak blocking and flyer plate extrusion, the flowing of the base and flyer plates generated the vortex structure where the ingot structure wrapping molten metals were observed; different levels of elemental diffusion took place near the bonding interfaces. The mechanical test results showed that the bending strength, tensile strength and microhardness peak value of the cladding plate were 288 MPa, 165.5 MPa and 227 HV, respectively, which met the requirements of industrial production.